Age-related changes in tissue macrophages precede cardiac functional impairment
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چکیده
منابع مشابه
Age-related changes in tissue macrophages precede cardiac functional impairment
Cardiac tissue macrophages (cTMs) are abundant in the murine heart but the extent to which the cTM phenotype changes with age is unknown. This study characterizes aging-dependent phenotypic changes in cTM subsets. Using theCx3cr1(GFP/+) mouse reporter line where GFP marks cTMs, and the tissue macrophage marker Mrc1, we show that two major cardiac tissue macrophage subsets, Mrc1-GFP(hi) and Mrc1...
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ژورنال
عنوان ژورنال: Aging
سال: 2014
ISSN: 1945-4589
DOI: 10.18632/aging.100669